Cylofold Homepage

RNA Secondary Structure Prediction with Pseudoknots

CyloFold is a program for predicting the secondary structure of an RNA sequence including pseudoknots. The usage is straightforward: after pasting a sequence in FASTA format or as plain text in the text field named "Sequence Data" one can click "submit" at the bottom of the page. For sequences greater 100 nucleotides, it is recommended to save the provided job ID, in order to be able to access the status of the job submission. Once the computation is finished, the predicted secondary structure is displayed in two different formats ("bracket-notation" as well as "CT-format").
This server was developed in the research group of Dr. Bruce A. Shapiro. This server is hosted by the Advanced Biomedical Computational Science (ABCS) of the National Cancer Institute (Frederick Campus).